From Chapter 1:
In this "Report" Hariot says of the tobacco plant: "There is an herbe which is sowed a part by itselfe and is called by the inhabitants Vppówoc: In the West Indies it hath divers names, according to the severall places and countries where it groweth and is used: The Spaniardes generally call it Tobacco. The leaves thereof being dried and brought into powder: they use to take the fume or smoke thereof by sucking it through pipes made of claie into their stomacke and heade: from whence it purgeth superfluous fleame and other grosse humors, openeth all the pores and passages of the body: by which meanes the use thereof, not only preserveth the body from obstructions: but if also any be, so that they have not beane of too long continuance, in short time breaketh them: wherby their bodies are notably preserved in health, and know not many greevous diseases wherewithall wee in England are oftentimes afflicted."

From Chapter 2:
In the afternoon the gallant might attend what Dekker calls a "Tobacco-ordinary," by which may possibly have been meant a smoking-club, or, more probably, the gathering after dinner at one of the many ordinaries in the neighbourhood of St. Paul's Cathedral of "tobacconists," as smokers were then called, to discuss the merits of their respective pipes, and of the various kinds of tobacco—"whether your Cane or your Pudding be sweetest."

Of course he often bragged, like Julio in Day's "Law Trickes": "Tobacco? the best in Europe, 't cost me ten Crownes an ounce, by this vapour."

From Chapter 1:
In the Wallace Collection at Hertford House is a pouch or case labelled as having belonged to and been used by Sir Walter Raleigh. This pouch contains several clay pipes. It was perhaps this same pouch or case which once upon a time figured in Ralph Thoresby's museum at Leeds, and is described by Thoresby himself in his "Ducatus Leodiensis," 1715. Curiously enough, a few years ago when excavations were being made around the foundations of Raleigh's house at Youghal a clay pipe-bowl was dug up which in size, shape, &c., was exactly like the pipes in the Wallace exhibit. Raleigh lived and no doubt smoked in the Youghal house, so it is quite possible that the bowl found belonged to one of the pipes actually smoked by him. In the garden of the Youghal house, by the way, they used to show the tree—perhaps still do so—under which Raleigh was sitting, smoking his pipe, when his servant drenched him. Thus the tradition, which, as we have seen, dates from 1708 only, has obtained two local habitations—Youghal and Durham House on the Adelphi site.

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."